Virtual screening against acetylcholine binding protein

• Main Authors: Maleeruk Utsintong, Piyanuch Rojsanga, Kwok Yiu Ho, Todd T. Talley, Arthur J. Olson, Kinzo Matsumoto, Opa Vajragupta
• Other Authors: University of Phayao
• Format: Article
• Published: 2018
• Subjects: Biochemistry, Genetics and Molecular Biology; Chemistry; Pharmacology, Toxicology and Pharmaceutics
• Online Access: https://repository.li.mahidol.ac.th/handle/123456789/13816
• Institution: Mahidol University

The nicotinic acetylcholine receptors (nAChRs) are a member of the ligand-gated ion channel family and play a key role in the transfer of information across neurological networks. The X-ray crystal structure of agonist-bound α7 acetylcholine binding protein (AChBP) has been recognized as the most ap...