The role of vascular endothelial growth factor A polymorphisms in breast cancer
Breast cancer is the most common cancer in females and the leading cause of cancer death in women worldwide. Angiogenesis, the formation of new blood vessels, plays an important role in the development and progression of breast cancer. Vascular endothelial growth factor A (VEGFA), the key modulator...
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th-mahidol.138522018-06-11T12:19:11Z The role of vascular endothelial growth factor A polymorphisms in breast cancer Doonyapat Sa-nguanraksa Pornchai O-charoenrat Mahidol University Biochemistry, Genetics and Molecular Biology Chemical Engineering Chemistry Computer Science Medicine Breast cancer is the most common cancer in females and the leading cause of cancer death in women worldwide. Angiogenesis, the formation of new blood vessels, plays an important role in the development and progression of breast cancer. Vascular endothelial growth factor A (VEGFA), the key modulator of angiogenesis, is highly expressed in cancer tissue and correlates with its more aggressive features. Polymorphisms of VEGFA alter the levels of expression and subsequently influence the susceptibility and aggressiveness of breast cancer. Assessment of VEGFA polymorphisms may be used for the identification of patients suitable for anti-VEGFA therapy. © 2012 by the authors; licensee MDPI, Basel, Switzerland. 2018-06-11T04:40:25Z 2018-06-11T04:40:25Z 2012-01-01 Review International Journal of Molecular Sciences. Vol.13, No.11 (2012), 14845-14864 10.3390/ijms131114845 14220067 16616596 2-s2.0-84870704754 https://repository.li.mahidol.ac.th/handle/123456789/13852 Mahidol University SCOPUS https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84870704754&origin=inward |
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Biochemistry, Genetics and Molecular Biology Chemical Engineering Chemistry Computer Science Medicine Doonyapat Sa-nguanraksa Pornchai O-charoenrat The role of vascular endothelial growth factor A polymorphisms in breast cancer |
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Breast cancer is the most common cancer in females and the leading cause of cancer death in women worldwide. Angiogenesis, the formation of new blood vessels, plays an important role in the development and progression of breast cancer. Vascular endothelial growth factor A (VEGFA), the key modulator of angiogenesis, is highly expressed in cancer tissue and correlates with its more aggressive features. Polymorphisms of VEGFA alter the levels of expression and subsequently influence the susceptibility and aggressiveness of breast cancer. Assessment of VEGFA polymorphisms may be used for the identification of patients suitable for anti-VEGFA therapy. © 2012 by the authors; licensee MDPI, Basel, Switzerland. |
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Mahidol University |
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Mahidol University Doonyapat Sa-nguanraksa Pornchai O-charoenrat |
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Review |
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Doonyapat Sa-nguanraksa Pornchai O-charoenrat |
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Doonyapat Sa-nguanraksa |
title |
The role of vascular endothelial growth factor A polymorphisms in breast cancer |
title_short |
The role of vascular endothelial growth factor A polymorphisms in breast cancer |
title_full |
The role of vascular endothelial growth factor A polymorphisms in breast cancer |
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The role of vascular endothelial growth factor A polymorphisms in breast cancer |
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The role of vascular endothelial growth factor A polymorphisms in breast cancer |
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role of vascular endothelial growth factor a polymorphisms in breast cancer |
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2018 |
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https://repository.li.mahidol.ac.th/handle/123456789/13852 |
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