The role of vascular endothelial growth factor A polymorphisms in breast cancer

Breast cancer is the most common cancer in females and the leading cause of cancer death in women worldwide. Angiogenesis, the formation of new blood vessels, plays an important role in the development and progression of breast cancer. Vascular endothelial growth factor A (VEGFA), the key modulator...

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Main Authors: Doonyapat Sa-nguanraksa, Pornchai O-charoenrat
Other Authors: Mahidol University
Format: Review
Published: 2018
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Online Access:https://repository.li.mahidol.ac.th/handle/123456789/13852
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spelling th-mahidol.138522018-06-11T12:19:11Z The role of vascular endothelial growth factor A polymorphisms in breast cancer Doonyapat Sa-nguanraksa Pornchai O-charoenrat Mahidol University Biochemistry, Genetics and Molecular Biology Chemical Engineering Chemistry Computer Science Medicine Breast cancer is the most common cancer in females and the leading cause of cancer death in women worldwide. Angiogenesis, the formation of new blood vessels, plays an important role in the development and progression of breast cancer. Vascular endothelial growth factor A (VEGFA), the key modulator of angiogenesis, is highly expressed in cancer tissue and correlates with its more aggressive features. Polymorphisms of VEGFA alter the levels of expression and subsequently influence the susceptibility and aggressiveness of breast cancer. Assessment of VEGFA polymorphisms may be used for the identification of patients suitable for anti-VEGFA therapy. © 2012 by the authors; licensee MDPI, Basel, Switzerland. 2018-06-11T04:40:25Z 2018-06-11T04:40:25Z 2012-01-01 Review International Journal of Molecular Sciences. Vol.13, No.11 (2012), 14845-14864 10.3390/ijms131114845 14220067 16616596 2-s2.0-84870704754 https://repository.li.mahidol.ac.th/handle/123456789/13852 Mahidol University SCOPUS https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84870704754&origin=inward
institution Mahidol University
building Mahidol University Library
continent Asia
country Thailand
Thailand
content_provider Mahidol University Library
collection Mahidol University Institutional Repository
topic Biochemistry, Genetics and Molecular Biology
Chemical Engineering
Chemistry
Computer Science
Medicine
spellingShingle Biochemistry, Genetics and Molecular Biology
Chemical Engineering
Chemistry
Computer Science
Medicine
Doonyapat Sa-nguanraksa
Pornchai O-charoenrat
The role of vascular endothelial growth factor A polymorphisms in breast cancer
description Breast cancer is the most common cancer in females and the leading cause of cancer death in women worldwide. Angiogenesis, the formation of new blood vessels, plays an important role in the development and progression of breast cancer. Vascular endothelial growth factor A (VEGFA), the key modulator of angiogenesis, is highly expressed in cancer tissue and correlates with its more aggressive features. Polymorphisms of VEGFA alter the levels of expression and subsequently influence the susceptibility and aggressiveness of breast cancer. Assessment of VEGFA polymorphisms may be used for the identification of patients suitable for anti-VEGFA therapy. © 2012 by the authors; licensee MDPI, Basel, Switzerland.
author2 Mahidol University
author_facet Mahidol University
Doonyapat Sa-nguanraksa
Pornchai O-charoenrat
format Review
author Doonyapat Sa-nguanraksa
Pornchai O-charoenrat
author_sort Doonyapat Sa-nguanraksa
title The role of vascular endothelial growth factor A polymorphisms in breast cancer
title_short The role of vascular endothelial growth factor A polymorphisms in breast cancer
title_full The role of vascular endothelial growth factor A polymorphisms in breast cancer
title_fullStr The role of vascular endothelial growth factor A polymorphisms in breast cancer
title_full_unstemmed The role of vascular endothelial growth factor A polymorphisms in breast cancer
title_sort role of vascular endothelial growth factor a polymorphisms in breast cancer
publishDate 2018
url https://repository.li.mahidol.ac.th/handle/123456789/13852
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