Artemether-lumefantrine treatment failure despite adequate lumefantrine day 7 concentration in a traveller with Plasmodium falciparum malaria after returning from Tanzania

• Main Authors: Anna Färnert, Johan Ursing, Thomas Tolfvenstam, Josea Rono, Lillemor Karlsson, Elda Sparrelid, Niklas Lindegårdh
• Other Authors: Karolinska Institutet
• Format: Article
• Published: 2018
• Subjects: Immunology and Microbiology; Medicine
• Online Access: https://repository.li.mahidol.ac.th/handle/123456789/14318
• Institution: Mahidol University

Artemether-lumefantrine is currently first-line therapy of Plasmodium falciparum malaria in many countries. This report describes a treatment failure despite adequate drug concentrations in a traveller returning from sub-Saharan Africa. Genotyping confirmed recrudescence and suggested reduced sensit...