Rapid and massive virus-specific plasmablast responses during acute: Dengue virus infection in humans

• Main Authors: Jens Wrammert, Nattawat Onlamoon, Rama S. Akondy, Guey C. Perng, Korakot Polsrila, Anmol Chandele, Marcin Kwissa, Bali Pulendran, Patrick C. Wilson, Orasri Wittawatmongkol, Sutee Yoksan, Nasikarn Angkasekwinai, Kovit Pattanapanyasat, Kulkanya Chokephaibulkit, Rafi Ahmed
• Other Authors: Emory University
• Format: Article
• Published: 2018
• Subjects: Immunology and Microbiology
• Online Access: https://repository.li.mahidol.ac.th/handle/123456789/14345
• Institution: Mahidol University

Humoral immune responses are thought to play a major role in dengue virus-induced immunopathology; however, little is known about the plasmablasts producing these antibodies during an ongoing infection. Herein we present an analysis of plasmablast responses in patients with acute dengue virus infect...