Role of francisella lipid A phosphate modification in virulence and long-term protective immune responses

Role of francisella lipid A phosphate modification in virulence and long-term protective immune responses

Lipopolysaccharide (LPS) structural modifications have been shown to specifically affect the pathogenesis of many Gramnegative pathogens. In Francisella, modification of the lipid A component of LPS resulted in a molecule with no to low endotoxic activity. The role of the terminal lipid A phosphates...

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Bibliographic Details
Main Authors: Duangjit Kanistanon, Daniel A. Powell, Adeline M. Hajjar, Mark R. Pelletier, Ilana E. Cohen, Sing Sing Way, Shawn J. Skerrett, Xiaoyuan Wang, Christian R H Raetz, Robert K. Ernst
Other Authors: Mahidol University
Format: Article
Published: 2018
Subjects:
Immunology and Microbiology
Medicine
Online Access:https://repository.li.mahidol.ac.th/handle/123456789/14355
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Institution: Mahidol University

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https://repository.li.mahidol.ac.th/handle/123456789/14355

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