A case series of refractory cutaneous sarcoidosis successfully treated with infliximab
Introduction: Sarcoidosis is a systemic granulomatous disease of unknown cause. The management of sarcoidosis remains problematic. Systemic and topical corticosteroids are the mainstay of therapy but may cause unacceptable side effects. Biologic therapies, such as infliximab, have recently beenpropo...
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th-mahidol.144122018-06-11T11:58:28Z A case series of refractory cutaneous sarcoidosis successfully treated with infliximab Papapit Tuchinda Matthew Bremmer Anthony A. Gaspari University of Maryland School of Medicine Mahidol University Medicine Introduction: Sarcoidosis is a systemic granulomatous disease of unknown cause. The management of sarcoidosis remains problematic. Systemic and topical corticosteroids are the mainstay of therapy but may cause unacceptable side effects. Biologic therapies, such as infliximab, have recently beenproposed asanother treatment option for cutaneous sarcoidosis. Case Report: The authors describe three patients who were diagnosed with cutaneous sarcoidosis with systemic involvement. All of the patients were refractory to conventional therapies but responded to infliximab therapy. Conclusion: Infliximab is an alternative medication for refractory sarcoidosis that has a relatively benign side-effect profile. However, definite indications, dosage, interval, and duration of treatment for cutaneous sarcoidosis are not firmly established. © The Author(s) 2012. 2018-06-11T04:58:28Z 2018-06-11T04:58:28Z 2012-12-20 Article Dermatology and Therapy. Vol.2, No.1 (2012), 1-9 10.1007/s13555-012-0011-9 21909172 2-s2.0-84871160440 https://repository.li.mahidol.ac.th/handle/123456789/14412 Mahidol University SCOPUS https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84871160440&origin=inward |
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Introduction: Sarcoidosis is a systemic granulomatous disease of unknown cause. The management of sarcoidosis remains problematic. Systemic and topical corticosteroids are the mainstay of therapy but may cause unacceptable side effects. Biologic therapies, such as infliximab, have recently beenproposed asanother treatment option for cutaneous sarcoidosis. Case Report: The authors describe three patients who were diagnosed with cutaneous sarcoidosis with systemic involvement. All of the patients were refractory to conventional therapies but responded to infliximab therapy. Conclusion: Infliximab is an alternative medication for refractory sarcoidosis that has a relatively benign side-effect profile. However, definite indications, dosage, interval, and duration of treatment for cutaneous sarcoidosis are not firmly established. © The Author(s) 2012. |
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University of Maryland School of Medicine |
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University of Maryland School of Medicine Papapit Tuchinda Matthew Bremmer Anthony A. Gaspari |
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Article |
author |
Papapit Tuchinda Matthew Bremmer Anthony A. Gaspari |
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Papapit Tuchinda |
title |
A case series of refractory cutaneous sarcoidosis successfully treated with infliximab |
title_short |
A case series of refractory cutaneous sarcoidosis successfully treated with infliximab |
title_full |
A case series of refractory cutaneous sarcoidosis successfully treated with infliximab |
title_fullStr |
A case series of refractory cutaneous sarcoidosis successfully treated with infliximab |
title_full_unstemmed |
A case series of refractory cutaneous sarcoidosis successfully treated with infliximab |
title_sort |
case series of refractory cutaneous sarcoidosis successfully treated with infliximab |
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2018 |
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https://repository.li.mahidol.ac.th/handle/123456789/14412 |
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