A case series of refractory cutaneous sarcoidosis successfully treated with infliximab

A case series of refractory cutaneous sarcoidosis successfully treated with infliximab

Introduction: Sarcoidosis is a systemic granulomatous disease of unknown cause. The management of sarcoidosis remains problematic. Systemic and topical corticosteroids are the mainstay of therapy but may cause unacceptable side effects. Biologic therapies, such as infliximab, have recently beenpropo...

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Main Authors: Papapit Tuchinda, Matthew Bremmer, Anthony A. Gaspari
Other Authors: University of Maryland School of Medicine
Format: Article
Published: 2018
Subjects:
Medicine
Online Access:https://repository.li.mahidol.ac.th/handle/123456789/14412
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Institution: Mahidol University
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spelling th-mahidol.144122018-06-11T11:58:28Z A case series of refractory cutaneous sarcoidosis successfully treated with infliximab Papapit Tuchinda Matthew Bremmer Anthony A. Gaspari University of Maryland School of Medicine Mahidol University Medicine Introduction: Sarcoidosis is a systemic granulomatous disease of unknown cause. The management of sarcoidosis remains problematic. Systemic and topical corticosteroids are the mainstay of therapy but may cause unacceptable side effects. Biologic therapies, such as infliximab, have recently beenproposed asanother treatment option for cutaneous sarcoidosis. Case Report: The authors describe three patients who were diagnosed with cutaneous sarcoidosis with systemic involvement. All of the patients were refractory to conventional therapies but responded to infliximab therapy. Conclusion: Infliximab is an alternative medication for refractory sarcoidosis that has a relatively benign side-effect profile. However, definite indications, dosage, interval, and duration of treatment for cutaneous sarcoidosis are not firmly established. © The Author(s) 2012. 2018-06-11T04:58:28Z 2018-06-11T04:58:28Z 2012-12-20 Article Dermatology and Therapy. Vol.2, No.1 (2012), 1-9 10.1007/s13555-012-0011-9 21909172 2-s2.0-84871160440 https://repository.li.mahidol.ac.th/handle/123456789/14412 Mahidol University SCOPUS https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84871160440&origin=inward
institution Mahidol University
building Mahidol University Library
continent Asia
country Thailand
Thailand
content_provider Mahidol University Library
collection Mahidol University Institutional Repository
topic Medicine
spellingShingle Medicine
Papapit Tuchinda
Matthew Bremmer
Anthony A. Gaspari
A case series of refractory cutaneous sarcoidosis successfully treated with infliximab
description Introduction: Sarcoidosis is a systemic granulomatous disease of unknown cause. The management of sarcoidosis remains problematic. Systemic and topical corticosteroids are the mainstay of therapy but may cause unacceptable side effects. Biologic therapies, such as infliximab, have recently beenproposed asanother treatment option for cutaneous sarcoidosis. Case Report: The authors describe three patients who were diagnosed with cutaneous sarcoidosis with systemic involvement. All of the patients were refractory to conventional therapies but responded to infliximab therapy. Conclusion: Infliximab is an alternative medication for refractory sarcoidosis that has a relatively benign side-effect profile. However, definite indications, dosage, interval, and duration of treatment for cutaneous sarcoidosis are not firmly established. © The Author(s) 2012.
author2 University of Maryland School of Medicine
author_facet University of Maryland School of Medicine
Papapit Tuchinda
Matthew Bremmer
Anthony A. Gaspari
format Article
author Papapit Tuchinda
Matthew Bremmer
Anthony A. Gaspari
author_sort Papapit Tuchinda
title A case series of refractory cutaneous sarcoidosis successfully treated with infliximab
title_short A case series of refractory cutaneous sarcoidosis successfully treated with infliximab
title_full A case series of refractory cutaneous sarcoidosis successfully treated with infliximab
title_fullStr A case series of refractory cutaneous sarcoidosis successfully treated with infliximab
title_full_unstemmed A case series of refractory cutaneous sarcoidosis successfully treated with infliximab
title_sort case series of refractory cutaneous sarcoidosis successfully treated with infliximab
publishDate 2018
url https://repository.li.mahidol.ac.th/handle/123456789/14412
_version_ 1763494535582711808

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