Red cell and platelet-derived microparticles are increased in G6PD-deficient subjects

• Main Authors: Duangdao Nantakomol, Attakorn Palasuwan, Mallika Chaowanathikhom, Suphan Soogarun, Mallika Imwong
• Other Authors: Chulalongkorn University
• Format: Article
• Published: 2018
• Subjects: Medicine
• Online Access: https://repository.li.mahidol.ac.th/handle/123456789/14560
• Institution: Mahidol University

In response to oxidative stress and during apoptosis, cells often shed microparticles (MPs), submicron elements carrying phosphatidylserine and protein antigens. Glucose-6-phosphate dehydrogenase (G6PD)-deficient cells are extremely sensitive to oxidative damage that may lead to the formation of MPs...