The second mini-transplant for unstable mixed chimerism within the first 100 days after hematopoietic stem cell transplant in severe thalassemia

• Main Authors: Worawut Choeyprasert, Samart Pakakasama, Usanarat Anurathapan, Duantida Songdej, Nongnuch Sirachainun, Somtawin Sirireung, Wanpen Panthangkool, Suradej Hongeng
• Other Authors: Mahidol University
• Format: Article
• Published: 2018
• Subjects: Medicine
• Online Access: https://repository.li.mahidol.ac.th/handle/123456789/14651

Allogeneic HSCT is the only curative treatment for severe thalassemia disease. MC occurs in one-third of these patients within the first two months after HSCT; this is a major risk factor of graft rejection, especially when RHCs are more than 25%. There is still no consensus for the management of MC...