Evaluation of myocardial deformation in patients with sickle cell disease and preserved ejection fraction using three-dimensional speckle tracking echocardiography

• Main Authors: Homaa Ahmad, Etienne Gayat, Chattanong Yodwut, M. Cristina Abduch, Amit R. Patel, Lynn Weinert, Ankit Desai, Wendy Tsang, Joe G N Garcia, Roberto M. Lang, Victor Mor-Avi
• Other Authors: University of Chicago
• Format: Article
• Published: 2018
• Subjects: Medicine
• Online Access: https://repository.li.mahidol.ac.th/handle/123456789/14674
• Institution: Mahidol University

Background: Sickle cell disease (SCD) is a hemoglobinopathy that affects one in 500 African Americans. Although it is well established that patients with SCD have left ventricular (LV) diastolic dysfunction, it is not clear whether they have subtle LV systolic dysfunction despite preserved ejection...