MAPK/ERK signaling in osteosarcomas, Ewing sarcomas and chondrosarcomas: Therapeutic implications and future directions

The introduction of cytotoxic chemotherapeutic drugs in the 1970s improved the survival rate of patients with bone sarcomas and allowed limb salvage surgeries. However, since the turn of the century, survival data has plateaued for a subset of metastatic, nonresponding osteo, and/or Ewing sarcomas....

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Bibliographic Details
Main Authors: Chandhanarat Chandhanayingyong, Yuhree Kim, J. Robert Staples, Cody Hahn, Francis Youngin Lee
Other Authors: Columbia University in the City of New York
Format: Review
Published: 2018
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Online Access:https://repository.li.mahidol.ac.th/handle/123456789/14804
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Institution: Mahidol University