Henoch–Schönlein purpura

© Heike Daldrup-Link and Beverley Newman 2014. Imaging description A seven-year-old boy presented with nausea and acute, colicky abdominal pain. The medical history revealed a pharyngitis a few weeks ago and the clinical examination demonstrated multiple small purpura (small areas of hemorrhage) of...

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Main Authors: Kriengkrai Iemsawatdikul, Heike E. Daldrup-Link
Other Authors: Mahidol University
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Published: 2018
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Online Access:https://repository.li.mahidol.ac.th/handle/123456789/15070
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spelling th-mahidol.150702018-06-11T12:19:16Z Henoch–Schönlein purpura Kriengkrai Iemsawatdikul Heike E. Daldrup-Link Mahidol University Stanford University Medicine © Heike Daldrup-Link and Beverley Newman 2014. Imaging description A seven-year-old boy presented with nausea and acute, colicky abdominal pain. The medical history revealed a pharyngitis a few weeks ago and the clinical examination demonstrated multiple small purpura (small areas of hemorrhage) of the skin of the buttocks and upper thighs. An upper gastrointestinal (GI) study demonstrated “thumbprinting” of the duodenum (Fig. 46.1). CT images from another patient after oral contrast media administration demonstrate marked mural thickening of a loop of ileum with narrowing of the lumen and some adjacent free fluid (Fig. 46.2). Importance. Henoch–Schönlein purpura is a disease of young children (50% are younger than six years of age and 90% are younger than 10 years of age), which typically occurs after an upper respiratory tract infection. The infection leads to formation of complexes of IgA and complement component 3, which accumulate in small vessels and cause a small-vessel vasculitis of the skin, joints, GI tract, and sometimes the kidneys. Acute GI symptoms may precede typical cutaneous lesions in 10–15% of patients and may lead to a laparotomy. It is important to recognize typical clinical and imaging findings of this disease, since it usually resolves spontaneously and does not require invasive interventions. 2018-06-11T05:19:16Z 2018-06-11T05:19:16Z 2012-01-01 Chapter Pearls and Pitfalls in Pediatric Imaging: Variants and Other Difficult Diagnoses. (2012), 205-206 10.1017/CBO9781139084239.047 2-s2.0-84923520100 https://repository.li.mahidol.ac.th/handle/123456789/15070 Mahidol University SCOPUS https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84923520100&origin=inward
institution Mahidol University
building Mahidol University Library
continent Asia
country Thailand
Thailand
content_provider Mahidol University Library
collection Mahidol University Institutional Repository
topic Medicine
spellingShingle Medicine
Kriengkrai Iemsawatdikul
Heike E. Daldrup-Link
Henoch–Schönlein purpura
description © Heike Daldrup-Link and Beverley Newman 2014. Imaging description A seven-year-old boy presented with nausea and acute, colicky abdominal pain. The medical history revealed a pharyngitis a few weeks ago and the clinical examination demonstrated multiple small purpura (small areas of hemorrhage) of the skin of the buttocks and upper thighs. An upper gastrointestinal (GI) study demonstrated “thumbprinting” of the duodenum (Fig. 46.1). CT images from another patient after oral contrast media administration demonstrate marked mural thickening of a loop of ileum with narrowing of the lumen and some adjacent free fluid (Fig. 46.2). Importance. Henoch–Schönlein purpura is a disease of young children (50% are younger than six years of age and 90% are younger than 10 years of age), which typically occurs after an upper respiratory tract infection. The infection leads to formation of complexes of IgA and complement component 3, which accumulate in small vessels and cause a small-vessel vasculitis of the skin, joints, GI tract, and sometimes the kidneys. Acute GI symptoms may precede typical cutaneous lesions in 10–15% of patients and may lead to a laparotomy. It is important to recognize typical clinical and imaging findings of this disease, since it usually resolves spontaneously and does not require invasive interventions.
author2 Mahidol University
author_facet Mahidol University
Kriengkrai Iemsawatdikul
Heike E. Daldrup-Link
format Chapter
author Kriengkrai Iemsawatdikul
Heike E. Daldrup-Link
author_sort Kriengkrai Iemsawatdikul
title Henoch–Schönlein purpura
title_short Henoch–Schönlein purpura
title_full Henoch–Schönlein purpura
title_fullStr Henoch–Schönlein purpura
title_full_unstemmed Henoch–Schönlein purpura
title_sort henoch–schönlein purpura
publishDate 2018
url https://repository.li.mahidol.ac.th/handle/123456789/15070
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