The genetic and molecular basis of O-antigenic diversity in Burkholderia pseudomallei lipopolysaccharide

• Main Authors: Apichai Tuanyok, Joshua K. Stone, Mark Mayo, Mirjam Kaestli, Jeffrey Gruendike, Shalamar Georgia, Stephanie Warrington, Travis Mullins, Christopher J. Allender, David M. Wagner, Narisara Chantratita, Sharon J. Peacock, Bart J. Currie, Paul Keim
• Other Authors: Northern Arizona University
• Format: Article
• Published: 2018
• Subjects: Medicine; Pharmacology, Toxicology and Pharmaceutics
• Online Access: https://repository.li.mahidol.ac.th/handle/123456789/15102
• Institution: Mahidol University

Lipopolysaccharide (LPS) is one of the most important virulence and antigenic components of Burkholderia pseudomallei, the causative agent of melioidosis. LPS diversity in B. pseudomallei has been described as typical, atypical or rough, based upon banding patterns on SDS-PAGE. Here, we studied the...