Dynamic Uptake of Radioactive Substance in Rat Salivary Gland Following <sup>3</sup>H‐Melatonin Administration
Dynamics of radioactive accumulation in rat greater salivary glfollowing systemic administration of 3 H‐melatonin was studied to determine a possible action of the hormone in the gland. Progressive decline of 3 H‐melatonin concentrations was found in the serum, lung, skeletal muscle, liver, kidney...
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| Main Authors: | , , |
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| Format: | Article |
| Published: |
2018
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| Online Access: | https://repository.li.mahidol.ac.th/handle/123456789/15319 |
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| Institution: | Mahidol University |
| Summary: | Dynamics of radioactive accumulation in rat greater salivary glfollowing systemic administration of 3 H‐melatonin was studied to determine a possible action of the hormone in the gland. Progressive decline of 3 H‐melatonin concentrations was found in the serum, lung, skeletal muscle, liver, kidney, salivary glduring 60 min following the administration. On the contrary, there was a progressive accumulation of radioactive substance other than 3 H‐melatonin in the salivary glbut not in other tissues mentioned. The radioactivity was also progressively preferentially localized in the nuclear fraction of the glcells. These results suggest a possible direct action of melatonin derivative in rat salivary gland. Copyright © 1987, Wiley Blackwell. All rights reserved |
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