Dynamic Alteration in Splenic Function during Acute falciparum Malaria

• Main Authors: Sornchai Looareesuwan, May ho, Yupaporn Wattanagoon, Nicholas J. White, David A. Warrell, Danai Bunnag, Tranakchit Harinasuta, David J. Wyler
• Other Authors: Mahidol University
• Format: Article
• Published: 2018
• Subjects: Medicine
• Online Access: https://repository.li.mahidol.ac.th/handle/123456789/15404

Plasmodium-infected erythrocytes lose their normal deformability and become susceptible to splenic filtration. In animal models, this is one mechanism of antimalarial defense. To assess the effect of acute falciparum malaria on splenic filtration, we measured the clearance of heated 51 Cr-labeled au...