Long‐Term Immunoprophylaxis of Hepatitis B Surface Antigen Carrier in Infants Born to Hepatitis B Surface Antigen Positive Mothers Using Plasma Derived Vaccine
Immunoprophylaxis of HBV infection using 3 doses (10 μg) of plasma derived HBV vaccine were given to 49 newborn infants of e‐antigen negative HBs Ag carrier mothers at birth, one and 6 months of age. The protective efficacy rate was 100% during first 2 years. At 3 years of age, HBs Ag carrier was 2....
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th-mahidol.158402018-06-14T16:15:54Z Long‐Term Immunoprophylaxis of Hepatitis B Surface Antigen Carrier in Infants Born to Hepatitis B Surface Antigen Positive Mothers Using Plasma Derived Vaccine Urusa Theppisai Chalermsri Thanuntaseth Pimol Chiewsilp Praput Siripoonya Mahidol University Medicine Immunoprophylaxis of HBV infection using 3 doses (10 μg) of plasma derived HBV vaccine were given to 49 newborn infants of e‐antigen negative HBs Ag carrier mothers at birth, one and 6 months of age. The protective efficacy rate was 100% during first 2 years. At 3 years of age, HBs Ag carrier was 2.63% and 89.48% of infants had anti‐HBs above the protective level. Ten point fifty‐two percent of total infants had anti‐HBs level below 10 mIU/ml and 21.05% had anti‐HBs level between 10–100 mIU/ml. Most infants who had the maximal level of antibody below 100 mIU/ml had lost all antibody within 3 years. The loss of antibody was closely related to the maximal anti‐HBs titer (one year of age) which is highly predictive indicator of the longevity of anti‐HBs. © 1989 Japanese Society of Obstetrics and Gynaecology 2018-06-14T09:15:54Z 2018-06-14T09:15:54Z 1989-01-01 Article Asia‐Oceania Journal of Obstetrics and Gynaecology. Vol.15, No.2 (1989), 111-115 10.1111/j.1447-0756.1989.tb00162.x 14470756 03892328 2-s2.0-0024678950 https://repository.li.mahidol.ac.th/handle/123456789/15840 Mahidol University SCOPUS https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=0024678950&origin=inward |
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Medicine Urusa Theppisai Chalermsri Thanuntaseth Pimol Chiewsilp Praput Siripoonya Long‐Term Immunoprophylaxis of Hepatitis B Surface Antigen Carrier in Infants Born to Hepatitis B Surface Antigen Positive Mothers Using Plasma Derived Vaccine |
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Immunoprophylaxis of HBV infection using 3 doses (10 μg) of plasma derived HBV vaccine were given to 49 newborn infants of e‐antigen negative HBs Ag carrier mothers at birth, one and 6 months of age. The protective efficacy rate was 100% during first 2 years. At 3 years of age, HBs Ag carrier was 2.63% and 89.48% of infants had anti‐HBs above the protective level. Ten point fifty‐two percent of total infants had anti‐HBs level below 10 mIU/ml and 21.05% had anti‐HBs level between 10–100 mIU/ml. Most infants who had the maximal level of antibody below 100 mIU/ml had lost all antibody within 3 years. The loss of antibody was closely related to the maximal anti‐HBs titer (one year of age) which is highly predictive indicator of the longevity of anti‐HBs. © 1989 Japanese Society of Obstetrics and Gynaecology |
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Mahidol University |
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Mahidol University Urusa Theppisai Chalermsri Thanuntaseth Pimol Chiewsilp Praput Siripoonya |
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Urusa Theppisai Chalermsri Thanuntaseth Pimol Chiewsilp Praput Siripoonya |
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Urusa Theppisai |
title |
Long‐Term Immunoprophylaxis of Hepatitis B Surface Antigen Carrier in Infants Born to Hepatitis B Surface Antigen Positive Mothers Using Plasma Derived Vaccine |
title_short |
Long‐Term Immunoprophylaxis of Hepatitis B Surface Antigen Carrier in Infants Born to Hepatitis B Surface Antigen Positive Mothers Using Plasma Derived Vaccine |
title_full |
Long‐Term Immunoprophylaxis of Hepatitis B Surface Antigen Carrier in Infants Born to Hepatitis B Surface Antigen Positive Mothers Using Plasma Derived Vaccine |
title_fullStr |
Long‐Term Immunoprophylaxis of Hepatitis B Surface Antigen Carrier in Infants Born to Hepatitis B Surface Antigen Positive Mothers Using Plasma Derived Vaccine |
title_full_unstemmed |
Long‐Term Immunoprophylaxis of Hepatitis B Surface Antigen Carrier in Infants Born to Hepatitis B Surface Antigen Positive Mothers Using Plasma Derived Vaccine |
title_sort |
long‐term immunoprophylaxis of hepatitis b surface antigen carrier in infants born to hepatitis b surface antigen positive mothers using plasma derived vaccine |
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2018 |
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https://repository.li.mahidol.ac.th/handle/123456789/15840 |
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1763487478215344128 |