Antiparasitic Drugs in Children
Many of the children living in tropical areas of the world are infected by a variety of human parasites. As a group, the antiparasitic drugs can claim to be the least studied of all compounds in current clinical use. There is little information on the disposition of these drugs in children, and most...
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th-mahidol.158762018-06-14T16:17:31Z Antiparasitic Drugs in Children Nicholas J. White Mahidol University Nuffield Department of Clinical Medicine Medicine Pharmacology, Toxicology and Pharmaceutics Many of the children living in tropical areas of the world are infected by a variety of human parasites. As a group, the antiparasitic drugs can claim to be the least studied of all compounds in current clinical use. There is little information on the disposition of these drugs in children, and most treatment recommendations are either empirical or by extrapolation from observations in adults. Many of the older drugs used in systemic parasitic infections have narrow therapeutic ratios and could be better used if treatment regimens were based on detailed pharmacokinetic and pharmacodynamic information. This review summarises existing information on these drugs and suggests provisional recommendations for antiparasitic treatment. © 1989, ADIS Press Limited. All rights reserved. 2018-06-14T09:16:48Z 2018-06-14T09:16:48Z 1989-01-01 Article Clinical Pharmacokinetics. Vol.17, No.1 (1989), 138-155 10.2165/00003088-198900171-00010 11791926 03125963 2-s2.0-0024836613 https://repository.li.mahidol.ac.th/handle/123456789/15876 Mahidol University SCOPUS https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=0024836613&origin=inward |
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Medicine Pharmacology, Toxicology and Pharmaceutics |
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Medicine Pharmacology, Toxicology and Pharmaceutics Nicholas J. White Antiparasitic Drugs in Children |
| description |
Many of the children living in tropical areas of the world are infected by a variety of human parasites. As a group, the antiparasitic drugs can claim to be the least studied of all compounds in current clinical use. There is little information on the disposition of these drugs in children, and most treatment recommendations are either empirical or by extrapolation from observations in adults. Many of the older drugs used in systemic parasitic infections have narrow therapeutic ratios and could be better used if treatment regimens were based on detailed pharmacokinetic and pharmacodynamic information. This review summarises existing information on these drugs and suggests provisional recommendations for antiparasitic treatment. © 1989, ADIS Press Limited. All rights reserved. |
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Mahidol University |
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Mahidol University Nicholas J. White |
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Article |
| author |
Nicholas J. White |
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Nicholas J. White |
| title |
Antiparasitic Drugs in Children |
| title_short |
Antiparasitic Drugs in Children |
| title_full |
Antiparasitic Drugs in Children |
| title_fullStr |
Antiparasitic Drugs in Children |
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Antiparasitic Drugs in Children |
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antiparasitic drugs in children |
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2018 |
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https://repository.li.mahidol.ac.th/handle/123456789/15876 |
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