Application of a mathematical model and Differential Evolution algorithm approach to optimization of bacteriocin production by Lactococcus lactis C7

• Main Authors: Sompop Moonchai, Weeranuch Madlhoo, Kanidtha Jariyachavalit, Hiroshi Shimizu, Suteaki Shioya, Somchai Chauvatcharin
• Other Authors: Mahidol University
• Format: Article
• Published: 2018
• Subjects: Biochemistry, Genetics and Molecular Biology; Chemical Engineering
• Online Access: https://repository.li.mahidol.ac.th/handle/123456789/16260

The effect of pH and temperature on cell growth and bacteriocin production in Lactococcus lactis C7 was investigated in order to optimize the production of bacteriocin. The study showed that the bacteriocin production was growth-associated, but declined after reaching the maximum titer. The decrease...