Improvement of function and morphology of tumor necrosis factor-α treated endothelial cells with 17-β estradiol - A preliminary study for a feasible simple model for atherosclerosis

• Main Authors: Parin Suwannaprapha, Urai Chaisri, Doungrat Riyong, Yaowapa Maneerat
• Other Authors: Mahidol University
• Format: Article
• Published: 2018
• Subjects: Biochemistry, Genetics and Molecular Biology; Medicine
• Online Access: https://repository.li.mahidol.ac.th/handle/123456789/16338

Background: Dysfunction of endothelial cells (EC) to produce endothelial nitric oxide synthase (eNOS) by tumor necrosis factor-α (TNF-α) causes critical features of vascular inflammation associated with several disease states (eg, atherosclerosis including increased platelet aggregation and adhesion...