A randomized trial of artemether-lumefantrine versus mefloquine-artesunate for the treatment of uncomplicated multi-drug resistant Plasmodium falciparum on the western border of Thailand

• Main Authors: Robert Hutagalung, Lucy Paiphun, Elizabeth A. Ashley, Rose McGready, Alan Brockman, Kaw L. Thwai, Pratap Singhasivanon, Thomas Jelinek, Nicholas J. White, François H. Nosten
• Other Authors: Shoklo Malaria Research Unit
• Format: Article
• Published: 2018
• Subjects: Immunology and Microbiology; Medicine
• Online Access: https://repository.li.mahidol.ac.th/handle/123456789/16552
• Institution: Mahidol University

Background: The use of antimalarial drug combinations with artemisinin derivatives is recommended to overcome drug resistance in Plasmodium falciparum. The fixed combination of oral artemether-lumefantrine, an artemisinin combination therapy (ACT) is highly effective and well tolerated. It is the on...