Open-label randomized trial of oral trimethoprim-sulfamethoxazole, doxycycline, and chloramphenicol compared with trimethoprim-sulfamethoxazole and doxycycline for maintenance therapy of melioidosis

Open-label randomized trial of oral trimethoprim-sulfamethoxazole, doxycycline, and chloramphenicol compared with trimethoprim-sulfamethoxazole and doxycycline for maintenance therapy of melioidosis

Melioidosis (infection caused by Burkholderia pseudomallei) requires a prolonged course of oral antibiotics following initial intravenous therapy to reduce the risk of relapse after cessation of treatment. The current recommendation is a four-drug regimen (trimethoprim [TMP], sulfamethoxazole [SMX],...

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Bibliographic Details
Main Authors: Wipada Chaowagul, Wirongrong Chierakul, Andrew J. Simpson, Jennifer M. Short, Kasia Stepniewska, Bina Maharjan, Adul Rajchanuvong, Duangkaew Busarawong, Direk Limmathurotsakul, Allen C. Cheng, Vanaporn Wuthiekanun, Paul N. Newton, Nicholas J. White, Nicholas P.J. Day, Sharon J. Peacock
Other Authors: Sappasitthiprasong Hospital
Format: Article
Published: 2018
Subjects:
Medicine
Pharmacology, Toxicology and Pharmaceutics
Online Access:https://repository.li.mahidol.ac.th/handle/123456789/16818
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Institution: Mahidol University

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https://repository.li.mahidol.ac.th/handle/123456789/16818

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