Anticardiolipin IgG antibody and homocysteine as possible risk factors for retinal vascular occlusive disease in Thai patients

Purpose: To assess the role of serum anticardiolipin IgG antibody and fasting plasma homocysteine levels as risk factors for retinal vascular occlusive disease in Thai patients. Methods: This is a retrospective, case-control study. Forty-one consecutive patients with recent onset of retinal vascular...

Full description

Saved in:
Bibliographic Details
Main Authors: La Ongsri Atchaneeyasakul, Adisak Trinavarat, Parapun Bumrungsuk, Warapat Wongsawad
Other Authors: Mahidol University
Format: Article
Published: 2018
Subjects:
Online Access:https://repository.li.mahidol.ac.th/handle/123456789/16981
Tags: Add Tag
No Tags, Be the first to tag this record!
Institution: Mahidol University
id th-mahidol.16981
record_format dspace
spelling th-mahidol.169812018-06-21T15:27:51Z Anticardiolipin IgG antibody and homocysteine as possible risk factors for retinal vascular occlusive disease in Thai patients La Ongsri Atchaneeyasakul Adisak Trinavarat Parapun Bumrungsuk Warapat Wongsawad Mahidol University Medicine Purpose: To assess the role of serum anticardiolipin IgG antibody and fasting plasma homocysteine levels as risk factors for retinal vascular occlusive disease in Thai patients. Methods: This is a retrospective, case-control study. Forty-one consecutive patients with recent onset of retinal vascular occlusive diseases were enrolled. In conjunction with a routine laboratory work up, serum anticardiolipin IgG antibody and plasma homocysteine were evaluated. Ninety volunteers without a history of retinal vascular occlusive disease were chosen as controls. Results: In general, mean levels of anticardiolipin IgG antibody and homocysteine did not differ between the patients and controls. However, when the groups without a history of underlying systemic diseases were compared, there were statistically significant differences in the anticardiolipin IgG antibody level between patients and controls (mean 12.24 ± 8.66 and 7.70 ± 6.69 GPL units/ml, respectively) with a P value of 0.024. Conclusions: No association was found between plasma homocysteine level and retinal vascular occlusion in our patient population. A high level of anticardiolipin IgG antibody is shown to be a risk factor only in patients without a history of underlying systemic diseases. The effect of anticardiolipin IgG antibody on the development of retinal vascular occlusive disease appears to be limited and may not be a major cause. © Japanese Ophthalmological Society 2005. 2018-06-21T08:27:51Z 2018-06-21T08:27:51Z 2005-05-01 Article Japanese Journal of Ophthalmology. Vol.49, No.3 (2005), 211-215 10.1007/s10384-005-0190-3 00215155 2-s2.0-21144437718 https://repository.li.mahidol.ac.th/handle/123456789/16981 Mahidol University SCOPUS https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=21144437718&origin=inward
institution Mahidol University
building Mahidol University Library
continent Asia
country Thailand
Thailand
content_provider Mahidol University Library
collection Mahidol University Institutional Repository
topic Medicine
spellingShingle Medicine
La Ongsri Atchaneeyasakul
Adisak Trinavarat
Parapun Bumrungsuk
Warapat Wongsawad
Anticardiolipin IgG antibody and homocysteine as possible risk factors for retinal vascular occlusive disease in Thai patients
description Purpose: To assess the role of serum anticardiolipin IgG antibody and fasting plasma homocysteine levels as risk factors for retinal vascular occlusive disease in Thai patients. Methods: This is a retrospective, case-control study. Forty-one consecutive patients with recent onset of retinal vascular occlusive diseases were enrolled. In conjunction with a routine laboratory work up, serum anticardiolipin IgG antibody and plasma homocysteine were evaluated. Ninety volunteers without a history of retinal vascular occlusive disease were chosen as controls. Results: In general, mean levels of anticardiolipin IgG antibody and homocysteine did not differ between the patients and controls. However, when the groups without a history of underlying systemic diseases were compared, there were statistically significant differences in the anticardiolipin IgG antibody level between patients and controls (mean 12.24 ± 8.66 and 7.70 ± 6.69 GPL units/ml, respectively) with a P value of 0.024. Conclusions: No association was found between plasma homocysteine level and retinal vascular occlusion in our patient population. A high level of anticardiolipin IgG antibody is shown to be a risk factor only in patients without a history of underlying systemic diseases. The effect of anticardiolipin IgG antibody on the development of retinal vascular occlusive disease appears to be limited and may not be a major cause. © Japanese Ophthalmological Society 2005.
author2 Mahidol University
author_facet Mahidol University
La Ongsri Atchaneeyasakul
Adisak Trinavarat
Parapun Bumrungsuk
Warapat Wongsawad
format Article
author La Ongsri Atchaneeyasakul
Adisak Trinavarat
Parapun Bumrungsuk
Warapat Wongsawad
author_sort La Ongsri Atchaneeyasakul
title Anticardiolipin IgG antibody and homocysteine as possible risk factors for retinal vascular occlusive disease in Thai patients
title_short Anticardiolipin IgG antibody and homocysteine as possible risk factors for retinal vascular occlusive disease in Thai patients
title_full Anticardiolipin IgG antibody and homocysteine as possible risk factors for retinal vascular occlusive disease in Thai patients
title_fullStr Anticardiolipin IgG antibody and homocysteine as possible risk factors for retinal vascular occlusive disease in Thai patients
title_full_unstemmed Anticardiolipin IgG antibody and homocysteine as possible risk factors for retinal vascular occlusive disease in Thai patients
title_sort anticardiolipin igg antibody and homocysteine as possible risk factors for retinal vascular occlusive disease in thai patients
publishDate 2018
url https://repository.li.mahidol.ac.th/handle/123456789/16981
_version_ 1763495277097910272