Anthelmintic effects of ethanolic extracts from pomegranate peels, mangosteen peels and tamarind seeds on gastrointestinal nematode egg counts in lambs

The anthelmintic drug resistance problems in animal husbandry are widely spread all over the world. The gastrointestinal nematodes in sheep economically impact on the decreasing of live-weight gain and body condition scores and have been recently resistant to many anthelmintics, especially albendazo...

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Main Authors: Pichai Bunviboolvat, Narisa Taechaarpornkul, Jeerapha Saratham, Sivapong Sungpradit, Charoonluk Jirapattharasate, Chowalit Nakthong, Lak Piasai, Orathai Thongjui, Sookruetai Boonmasawai
Other Authors: Mahidol University. Faculty of Veterinary Science. Department of Pre-clinic and Applied Animal Science
Format: Article
Language:English
Published: 2016
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Online Access:https://repository.li.mahidol.ac.th/handle/123456789/1711
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spelling th-mahidol.17112023-04-12T15:26:21Z Anthelmintic effects of ethanolic extracts from pomegranate peels, mangosteen peels and tamarind seeds on gastrointestinal nematode egg counts in lambs ผลของสารสกัดด้วยเอทานอลจากเปลือกทับทิม เปลือกมังคุด และเมล็ดมะขามที่มีต่อจำนวนไข่พยาธิตัวกลมในทางเดินอาหารของลูกแกะ Pichai Bunviboolvat Narisa Taechaarpornkul Jeerapha Saratham Sivapong Sungpradit Charoonluk Jirapattharasate Chowalit Nakthong Lak Piasai Orathai Thongjui Sookruetai Boonmasawai Mahidol University. Faculty of Veterinary Science. Department of Pre-clinic and Applied Animal Science Mahidol University. Faculty of Veterinay Science. Department of Clinical Sciences and Public Health Kasetsart University. Small Ruminant R&D Center Mahidol University. Faculty of Veterinary Science. The Center for Veterinary Diagnosis pomegranate peels mangosteen peels tamarind seeds gastrointestinal nematode lamb เปลือกผลทับทิม เปลือกผลมังคุด เมล็ดมะขาม พยาธิตัวกลมในทางเดินอาหาร ลูกแกะ Open Access article The anthelmintic drug resistance problems in animal husbandry are widely spread all over the world. The gastrointestinal nematodes in sheep economically impact on the decreasing of live-weight gain and body condition scores and have been recently resistant to many anthelmintics, especially albendazole, levamisole, macrocyclic lactone, moxidectin and ivermectin. Therefore, the herbal medicine is the one of alternative anthelmintic ways to solve chemical resistance and economic problems in small ruminant farms. This study was aimed to investigate the effects of pomegranate (Punica granatum L.) peels, mangosteen (Garcinia mangostana) peels and tamarind (Tamarindus indica) seeds extracts on gastrointestinal nematode egg counts in lambs comparing with albendazole and ivermectin. The results were shown that ivermectin could not decrease egg counted number significantly, but albendazole could significantly decrease percent of the egg per gram (EPG) when compared with pre-treatment (day 0) at day 1 (68±9%), day 3 (53±10%) and day 7 (62±8%). At day 1, the ethanolic extract of pomegranate peels and tamarind seed were significantly effect on gastrointestinal nematode egg count (47±8% and 48±10%, respectively). EPG were not affected by mangosteen peels extract. Serum alanine aminotransferase (ALT) (8-17.8 IU/L), aspartate aminotransferase (AST) (88.5-127.3 IU/L), creatinine (0.7-0.9 mg/dl) and blood urea nitrogen (BUN) (11-18.5 mg/dl) value after treatment were also normal and the lambs did not express any clinical renal or hepatic symptoms. It is concluded that the ethanolic extracts of pomegranate peels, and tamarind seeds possess significant anthelmintic activities at day 1 and could be a potential alternative for management of gastrointestinal roundworm problem in lambs. 2016-04-19T03:37:03Z 2017-04-10T10:03:27Z 2016-04-19T03:37:03Z 2017-04-10T10:03:27Z 2016-04-19 2013 Research Article Journal of Applied Animal Science. Vol.6, No.2 (May-Aug 2013), 39-50 1906-2257 https://repository.li.mahidol.ac.th/handle/123456789/1711 eng Mahidol University Faculty of Veterinary Science Mahidol University application/pdf
institution Mahidol University
building Mahidol University Library
continent Asia
country Thailand
Thailand
content_provider Mahidol University Library
collection Mahidol University Institutional Repository
language English
topic pomegranate peels
mangosteen peels
tamarind seeds
gastrointestinal nematode
lamb
เปลือกผลทับทิม
เปลือกผลมังคุด
เมล็ดมะขาม
พยาธิตัวกลมในทางเดินอาหาร
ลูกแกะ
Open Access article
spellingShingle pomegranate peels
mangosteen peels
tamarind seeds
gastrointestinal nematode
lamb
เปลือกผลทับทิม
เปลือกผลมังคุด
เมล็ดมะขาม
พยาธิตัวกลมในทางเดินอาหาร
ลูกแกะ
Open Access article
Pichai Bunviboolvat
Narisa Taechaarpornkul
Jeerapha Saratham
Sivapong Sungpradit
Charoonluk Jirapattharasate
Chowalit Nakthong
Lak Piasai
Orathai Thongjui
Sookruetai Boonmasawai
Anthelmintic effects of ethanolic extracts from pomegranate peels, mangosteen peels and tamarind seeds on gastrointestinal nematode egg counts in lambs
description The anthelmintic drug resistance problems in animal husbandry are widely spread all over the world. The gastrointestinal nematodes in sheep economically impact on the decreasing of live-weight gain and body condition scores and have been recently resistant to many anthelmintics, especially albendazole, levamisole, macrocyclic lactone, moxidectin and ivermectin. Therefore, the herbal medicine is the one of alternative anthelmintic ways to solve chemical resistance and economic problems in small ruminant farms. This study was aimed to investigate the effects of pomegranate (Punica granatum L.) peels, mangosteen (Garcinia mangostana) peels and tamarind (Tamarindus indica) seeds extracts on gastrointestinal nematode egg counts in lambs comparing with albendazole and ivermectin. The results were shown that ivermectin could not decrease egg counted number significantly, but albendazole could significantly decrease percent of the egg per gram (EPG) when compared with pre-treatment (day 0) at day 1 (68±9%), day 3 (53±10%) and day 7 (62±8%). At day 1, the ethanolic extract of pomegranate peels and tamarind seed were significantly effect on gastrointestinal nematode egg count (47±8% and 48±10%, respectively). EPG were not affected by mangosteen peels extract. Serum alanine aminotransferase (ALT) (8-17.8 IU/L), aspartate aminotransferase (AST) (88.5-127.3 IU/L), creatinine (0.7-0.9 mg/dl) and blood urea nitrogen (BUN) (11-18.5 mg/dl) value after treatment were also normal and the lambs did not express any clinical renal or hepatic symptoms. It is concluded that the ethanolic extracts of pomegranate peels, and tamarind seeds possess significant anthelmintic activities at day 1 and could be a potential alternative for management of gastrointestinal roundworm problem in lambs.
author2 Mahidol University. Faculty of Veterinary Science. Department of Pre-clinic and Applied Animal Science
author_facet Mahidol University. Faculty of Veterinary Science. Department of Pre-clinic and Applied Animal Science
Pichai Bunviboolvat
Narisa Taechaarpornkul
Jeerapha Saratham
Sivapong Sungpradit
Charoonluk Jirapattharasate
Chowalit Nakthong
Lak Piasai
Orathai Thongjui
Sookruetai Boonmasawai
format Article
author Pichai Bunviboolvat
Narisa Taechaarpornkul
Jeerapha Saratham
Sivapong Sungpradit
Charoonluk Jirapattharasate
Chowalit Nakthong
Lak Piasai
Orathai Thongjui
Sookruetai Boonmasawai
author_sort Pichai Bunviboolvat
title Anthelmintic effects of ethanolic extracts from pomegranate peels, mangosteen peels and tamarind seeds on gastrointestinal nematode egg counts in lambs
title_short Anthelmintic effects of ethanolic extracts from pomegranate peels, mangosteen peels and tamarind seeds on gastrointestinal nematode egg counts in lambs
title_full Anthelmintic effects of ethanolic extracts from pomegranate peels, mangosteen peels and tamarind seeds on gastrointestinal nematode egg counts in lambs
title_fullStr Anthelmintic effects of ethanolic extracts from pomegranate peels, mangosteen peels and tamarind seeds on gastrointestinal nematode egg counts in lambs
title_full_unstemmed Anthelmintic effects of ethanolic extracts from pomegranate peels, mangosteen peels and tamarind seeds on gastrointestinal nematode egg counts in lambs
title_sort anthelmintic effects of ethanolic extracts from pomegranate peels, mangosteen peels and tamarind seeds on gastrointestinal nematode egg counts in lambs
publishDate 2016
url https://repository.li.mahidol.ac.th/handle/123456789/1711
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