Prognostic significance of quantitative bacteremia in septicemic melioidosis
Pour-plate blood cultures were performed for 418 adult patients with suspected septicemic melioidosis in order to determine the relationship between quantitative bacterial counts in blood and mortality. Of 108 patients whose hemocultures yielded Burkholderia pseudomallei, 53% had <10 cfulmL and 2...
Saved in:
Main Authors: | , , , , , , , |
---|---|
Other Authors: | |
Format: | Note |
Published: |
2018
|
Subjects: | |
Online Access: | https://repository.li.mahidol.ac.th/handle/123456789/17492 |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Institution: | Mahidol University |
id |
th-mahidol.17492 |
---|---|
record_format |
dspace |
spelling |
th-mahidol.174922018-07-04T14:01:19Z Prognostic significance of quantitative bacteremia in septicemic melioidosis Amanda L. Walsh Michael D. Smith Vanaporn Wuthiekanun Yupin Suputtamongkol Wipada Chaowagul David A.B. Dance Brian Angus Nicholas J. White Mahidol University Nuffield Department of Clinical Medicine Derriford Hospital Medicine Pour-plate blood cultures were performed for 418 adult patients with suspected septicemic melioidosis in order to determine the relationship between quantitative bacterial counts in blood and mortality. Of 108 patients whose hemocultures yielded Burkholderia pseudomallei, 53% had <10 cfulmL and 24% had > 100 cfulmL. High blood bacterial counts were more common than reported previously with regard to other gram-negative septicemias and weresignificantly associated with the development ofhypotension (P =.008) and a fatal outcome (P =.0001). The overall mortality was 63% (95% CI, 53%-72%); however, counts of ≤1 cfulmL were associated with a mortality of 42% (95% CI, 28%-58%), compared with 96% (95% CI, 80%-100%) with counts of >100 cfu/mL. Heavy bacteremia (>50cfulmL) is common in septicemic melioidosis and is usually fatal. © 1995 The University of Chicago. 2018-07-04T07:01:19Z 2018-07-04T07:01:19Z 1995-01-01 Note Clinical Infectious Diseases. Vol.21, No.6 (1995), 1498-1500 10.1093/clinids/21.6.1498 15376591 10584838 2-s2.0-0029616026 https://repository.li.mahidol.ac.th/handle/123456789/17492 Mahidol University SCOPUS https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=0029616026&origin=inward |
institution |
Mahidol University |
building |
Mahidol University Library |
continent |
Asia |
country |
Thailand Thailand |
content_provider |
Mahidol University Library |
collection |
Mahidol University Institutional Repository |
topic |
Medicine |
spellingShingle |
Medicine Amanda L. Walsh Michael D. Smith Vanaporn Wuthiekanun Yupin Suputtamongkol Wipada Chaowagul David A.B. Dance Brian Angus Nicholas J. White Prognostic significance of quantitative bacteremia in septicemic melioidosis |
description |
Pour-plate blood cultures were performed for 418 adult patients with suspected septicemic melioidosis in order to determine the relationship between quantitative bacterial counts in blood and mortality. Of 108 patients whose hemocultures yielded Burkholderia pseudomallei, 53% had <10 cfulmL and 24% had > 100 cfulmL. High blood bacterial counts were more common than reported previously with regard to other gram-negative septicemias and weresignificantly associated with the development ofhypotension (P =.008) and a fatal outcome (P =.0001). The overall mortality was 63% (95% CI, 53%-72%); however, counts of ≤1 cfulmL were associated with a mortality of 42% (95% CI, 28%-58%), compared with 96% (95% CI, 80%-100%) with counts of >100 cfu/mL. Heavy bacteremia (>50cfulmL) is common in septicemic melioidosis and is usually fatal. © 1995 The University of Chicago. |
author2 |
Mahidol University |
author_facet |
Mahidol University Amanda L. Walsh Michael D. Smith Vanaporn Wuthiekanun Yupin Suputtamongkol Wipada Chaowagul David A.B. Dance Brian Angus Nicholas J. White |
format |
Note |
author |
Amanda L. Walsh Michael D. Smith Vanaporn Wuthiekanun Yupin Suputtamongkol Wipada Chaowagul David A.B. Dance Brian Angus Nicholas J. White |
author_sort |
Amanda L. Walsh |
title |
Prognostic significance of quantitative bacteremia in septicemic melioidosis |
title_short |
Prognostic significance of quantitative bacteremia in septicemic melioidosis |
title_full |
Prognostic significance of quantitative bacteremia in septicemic melioidosis |
title_fullStr |
Prognostic significance of quantitative bacteremia in septicemic melioidosis |
title_full_unstemmed |
Prognostic significance of quantitative bacteremia in septicemic melioidosis |
title_sort |
prognostic significance of quantitative bacteremia in septicemic melioidosis |
publishDate |
2018 |
url |
https://repository.li.mahidol.ac.th/handle/123456789/17492 |
_version_ |
1763495225327616000 |