The induction of cyclo-oxygenase-2 in human pulmonary epithelial cell culture (A549) activated by IL-1β is inhibited by tyrosine kinase inhibitors

Cyclo-oxygenase (COX) exists as two isoforms. In endothelial cells, the induction of COX (COX-2) elicited by endotoxin or inflammatory cytokines is mediated by tyrosine kinase. Here we have investigated whether the induction of COX-2 elicited by IL-1β in human pulmonary epithelial cells (A549) is me...

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Bibliographic Details
Main Authors: P. Akarasereenont, C. Thiemermann
Other Authors: Barts and The London Queen Mary's School of Medicine and Dentistry
Format: Article
Published: 2018
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Online Access:https://repository.li.mahidol.ac.th/handle/123456789/17546
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Institution: Mahidol University