A study of cell-mediated immune response to pancreatic antigens in patients with fibrocalculous pancreatic diabetes
In order to investigate whether there was any association between autoimmunity to pancreatic antigens with FCPD as well as IDDM, cell-mediated immune response to pancreatic antigens was studied by lymphoproliferation assay in 7 FCPD, 17 IDDM, 33 NIDDM patients and 102 normal controls. Optimal pancre...
Saved in:
Main Authors: | , , , |
---|---|
Other Authors: | |
Format: | Article |
Published: |
2018
|
Subjects: | |
Online Access: | https://repository.li.mahidol.ac.th/handle/123456789/17609 |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Institution: | Mahidol University |
id |
th-mahidol.17609 |
---|---|
record_format |
dspace |
spelling |
th-mahidol.176092018-07-04T14:27:22Z A study of cell-mediated immune response to pancreatic antigens in patients with fibrocalculous pancreatic diabetes Napatawn Tandhanand-Banchuin Wannapa Kespichayawatana Sathit Vannasaeng Suttipant Sarasombath Mahidol University Immunology and Microbiology Medicine In order to investigate whether there was any association between autoimmunity to pancreatic antigens with FCPD as well as IDDM, cell-mediated immune response to pancreatic antigens was studied by lymphoproliferation assay in 7 FCPD, 17 IDDM, 33 NIDDM patients and 102 normal controls. Optimal pancreatic antigen concentrations used were 100, 150 and 200 μg/ml. Positive results were considered for each concentration of antigens tested, at stimulation index (SI) > (mean ± 2 SD) SI obtained from normal age-matched controls with the use of the corresponding concentration of antigen. The one who gave positive result with any of these optimal antigen concentrations was considered to be the responder to pancreatic antigens. With this criterion, the responders were found to be 3/7 (42.9%) FCPD, 6/17 (35.3%) IDDM and 6/33 (18.2%) NIDDM patients; while there were 11 of all 102 (10.8%) normal controls. 2018-07-04T07:24:30Z 2018-07-04T07:24:30Z 1996-12-01 Article Asian Pacific Journal of Allergy and Immunology. Vol.14, No.2 (1996), 91-97 0125877X 2-s2.0-0030429672 https://repository.li.mahidol.ac.th/handle/123456789/17609 Mahidol University SCOPUS https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=0030429672&origin=inward |
institution |
Mahidol University |
building |
Mahidol University Library |
continent |
Asia |
country |
Thailand Thailand |
content_provider |
Mahidol University Library |
collection |
Mahidol University Institutional Repository |
topic |
Immunology and Microbiology Medicine |
spellingShingle |
Immunology and Microbiology Medicine Napatawn Tandhanand-Banchuin Wannapa Kespichayawatana Sathit Vannasaeng Suttipant Sarasombath A study of cell-mediated immune response to pancreatic antigens in patients with fibrocalculous pancreatic diabetes |
description |
In order to investigate whether there was any association between autoimmunity to pancreatic antigens with FCPD as well as IDDM, cell-mediated immune response to pancreatic antigens was studied by lymphoproliferation assay in 7 FCPD, 17 IDDM, 33 NIDDM patients and 102 normal controls. Optimal pancreatic antigen concentrations used were 100, 150 and 200 μg/ml. Positive results were considered for each concentration of antigens tested, at stimulation index (SI) > (mean ± 2 SD) SI obtained from normal age-matched controls with the use of the corresponding concentration of antigen. The one who gave positive result with any of these optimal antigen concentrations was considered to be the responder to pancreatic antigens. With this criterion, the responders were found to be 3/7 (42.9%) FCPD, 6/17 (35.3%) IDDM and 6/33 (18.2%) NIDDM patients; while there were 11 of all 102 (10.8%) normal controls. |
author2 |
Mahidol University |
author_facet |
Mahidol University Napatawn Tandhanand-Banchuin Wannapa Kespichayawatana Sathit Vannasaeng Suttipant Sarasombath |
format |
Article |
author |
Napatawn Tandhanand-Banchuin Wannapa Kespichayawatana Sathit Vannasaeng Suttipant Sarasombath |
author_sort |
Napatawn Tandhanand-Banchuin |
title |
A study of cell-mediated immune response to pancreatic antigens in patients with fibrocalculous pancreatic diabetes |
title_short |
A study of cell-mediated immune response to pancreatic antigens in patients with fibrocalculous pancreatic diabetes |
title_full |
A study of cell-mediated immune response to pancreatic antigens in patients with fibrocalculous pancreatic diabetes |
title_fullStr |
A study of cell-mediated immune response to pancreatic antigens in patients with fibrocalculous pancreatic diabetes |
title_full_unstemmed |
A study of cell-mediated immune response to pancreatic antigens in patients with fibrocalculous pancreatic diabetes |
title_sort |
study of cell-mediated immune response to pancreatic antigens in patients with fibrocalculous pancreatic diabetes |
publishDate |
2018 |
url |
https://repository.li.mahidol.ac.th/handle/123456789/17609 |
_version_ |
1763493822414716928 |