Incidence and non-drug aetiologies of aplastic anaemia in Thailand
A population-based, case-control study of aplastic anaemia has been conducted in Thailand since 1989. Up to December 1994, the overall annual incidence was 3.9/106 in Bangkok, 5.0/106 in Khonkaen and 3.0/106 in Songkla. In Bangkok, the incidence peaked in 2 age groups (at 15-24 yr and ≤60 yr), where...
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| Main Authors: | , , |
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| Format: | Conference or Workshop Item |
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2018
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| Online Access: | https://repository.li.mahidol.ac.th/handle/123456789/17653 |
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| Institution: | Mahidol University |
| Summary: | A population-based, case-control study of aplastic anaemia has been conducted in Thailand since 1989. Up to December 1994, the overall annual incidence was 3.9/106 in Bangkok, 5.0/106 in Khonkaen and 3.0/106 in Songkla. In Bangkok, the incidence peaked in 2 age groups (at 15-24 yr and ≤60 yr), whereas in Khonkaen and Songkla there was a consistent increase in incidence with increasing age. The results of case-control analyses for non-drug risk factors indicate a strong inverse association with socio-economic status present in all 3 areas; a strong association with grain farming in the 2 rural areas that does not appear to be explained by pesticides; an association with occupational exposure to solvents in Bangkok; and a positive association with hepatitis A seropositivity. |
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