Enhanced dissolution of ursodeoxycholic acid from the solid dispersion
Solid dispersions of a very slightly water-soluble drug, ursodeoxycholic acid (UDCA), were prepared using urea, mannitol, and PEG 6000 as a carrier, and the solubility of UDCA was determined in water-ethanol (I:I) mixed solvent as a function of UDCA-carrier ratio. The solubility of UDCA was slightly...
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| Main Authors: | , , , , |
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| Other Authors: | |
| Format: | Article |
| Published: |
2018
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| Subjects: | |
| Online Access: | https://repository.li.mahidol.ac.th/handle/123456789/17939 |
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| Institution: | Mahidol University |