Glutathione Redox system in Beta-Thalassemia/Hb E patients

• Main Authors: Kalpravidh, Ruchaneekorn W., Thongchai Tangjaidee, Suneerat Hatairaktham, Ratiya Charoensakdi, Narumol Panichkul, Noppadol Siritanaratkul, Suthat Fucharoen
• Other Authors: Mahidol University. Institute of Molecular Biosciences. Thalassemia Research Center
• Format: Article
• Language: English
• Published: 2015
• Subjects: Glutathione; Redox System; -Thalassemia; Hb E Patients; Open Access article
• Online Access: http://dx.doi.org/10.1155/2013/543973; https://repository.li.mahidol.ac.th/handle/123456789/1803
• Institution: Mahidol University

β-thalassemia/Hb E is known to cause oxidative stress induced by iron overload. The glutathione system is the major endogenous antioxidant that protects animal cells from oxidative damage. This study aimed to determine the effect of disease state and splenectomy on redox status expressed by whole bl...