Amphetamine and pseudoephedrine cross-tolerance measured by c-Fos protein expression in brains of chronically treated rats

• Main Authors: Nootchanart Ruksee, Walaiporn Tongjaroenbuangam, Stefano O Casalotti, Piyarat Govitrapong
• Format: Article
• Language: English
• Published: 2012
• Subjects: Dopamine Uptake Inhibitors; Nasal Decongestants; Proto-Oncogene Proteins c-fos; Amphetamine; Pseudoephedrine; Open Access article
• Online Access: https://repository.li.mahidol.ac.th/handle/123456789/1807
• Institution: Mahidol University

Background: Pseudoephedrine is a drug commonly prescribed as a nasal decongestant and bronchodilator and is also freely available in cold remedies and medications. The structural and pharmacological similarity of pseudoephedrine to amphetamine has led to evaluation of its psychomotor stimulant pr...