A dot-ELISA test using monoclonal antibody-purified antigens for the diagnosis of paragonimiasis caused by paragonimus heterotremus

A dot-ELISA test using monoclonal antibody-purified antigens for the diagnosis of paragonimiasis caused by paragonimus heterotremus

A dot enzyme-linked immunosorbent assay (dot-ELISA) using antigens purified by monoclonal antibody-affinity chromatography was developed for detecting antibodies to Paragonimus heterotremus in four groups of subjects. They consisted of 30 patients with P. heterotremus infection, 93 patients with oth...

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Bibliographic Details
Main Authors: Wanchai Maleewong, Pewpan M. Intapan, Chaisiri Wongkham, Mongkol Pajongthanasaris, Nimit Morakote, Pramuan Tapchaisri, Wanpen Chaicumpa
Other Authors: Khon Kaen University
Format: Article
Published: 2018
Subjects:
Medicine
Online Access:https://repository.li.mahidol.ac.th/handle/123456789/18094
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Institution: Mahidol University
Description
Summary:A dot enzyme-linked immunosorbent assay (dot-ELISA) using antigens purified by monoclonal antibody-affinity chromatography was developed for detecting antibodies to Paragonimus heterotremus in four groups of subjects. They consisted of 30 patients with P. heterotremus infection, 93 patients with other parasito infections, 18 patients with pulmonary tuberculosis and 30 normal, healthy controls. Sensitivity, specificity, as well as positive and negative predictive values of the test were 100, 97, 88, and 100%, respectively.

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