Osteosarcoma : A Study of 130 Cases
Multidisciplinary treatment of osteosarcoma in the Faculty of Medicine Ramathibodi Hospital, Mahidol University, using preoperative intraarterial and postoperative chemotherapy, with or without local irradiation, combined with surgery and prophylactic lung irradiation provided an excellent 5 years...
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th-mahidol.181812018-07-04T14:51:58Z Osteosarcoma : A Study of 130 Cases Lucksana Pochanugool Daungjai Sangthawan Thanya Subhadharaphandou Somjai Dangprasert Phongjan Hathirat Vorachai Sirikulchayanonta Vorachai Ratanatharathorn Chirapha Tannanonta Supron Onsanit Porntip Yuktanonda Mahidol University Medicine Multidisciplinary treatment of osteosarcoma in the Faculty of Medicine Ramathibodi Hospital, Mahidol University, using preoperative intraarterial and postoperative chemotherapy, with or without local irradiation, combined with surgery and prophylactic lung irradiation provided an excellent 5 years' survival of 55 per cent, the same rate as the 9 years' survival. The survival was stable after 4.4 years. The patients with local irradiation had more tumor destruction apparent on the surgical specimen. The administration of prophylactic whole lung irradiation provided an outcome without any undesirable complication. Sixteen per cent of the cases with PLI developed lung metastasis compared to 48 per cent without PLI. The most important prognostic factor was low level of serum lactic acid dehydrogenase. The unanswered question is what is the optimal treatment for osteosarcoma? 2018-07-04T07:51:58Z 2018-07-04T07:51:58Z 1997-01-01 Article Journal of the Medical Association of Thailand. Vol.80, No.3 (1997), 152-158 01252208 2-s2.0-2442460102 https://repository.li.mahidol.ac.th/handle/123456789/18181 Mahidol University SCOPUS https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=2442460102&origin=inward |
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Medicine Lucksana Pochanugool Daungjai Sangthawan Thanya Subhadharaphandou Somjai Dangprasert Phongjan Hathirat Vorachai Sirikulchayanonta Vorachai Ratanatharathorn Chirapha Tannanonta Supron Onsanit Porntip Yuktanonda Osteosarcoma : A Study of 130 Cases |
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Multidisciplinary treatment of osteosarcoma in the Faculty of Medicine Ramathibodi Hospital, Mahidol University, using preoperative intraarterial and postoperative chemotherapy, with or without local irradiation, combined with surgery and prophylactic lung irradiation provided an excellent 5 years' survival of 55 per cent, the same rate as the 9 years' survival. The survival was stable after 4.4 years. The patients with local irradiation had more tumor destruction apparent on the surgical specimen. The administration of prophylactic whole lung irradiation provided an outcome without any undesirable complication. Sixteen per cent of the cases with PLI developed lung metastasis compared to 48 per cent without PLI. The most important prognostic factor was low level of serum lactic acid dehydrogenase. The unanswered question is what is the optimal treatment for osteosarcoma? |
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Mahidol University |
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Mahidol University Lucksana Pochanugool Daungjai Sangthawan Thanya Subhadharaphandou Somjai Dangprasert Phongjan Hathirat Vorachai Sirikulchayanonta Vorachai Ratanatharathorn Chirapha Tannanonta Supron Onsanit Porntip Yuktanonda |
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Lucksana Pochanugool Daungjai Sangthawan Thanya Subhadharaphandou Somjai Dangprasert Phongjan Hathirat Vorachai Sirikulchayanonta Vorachai Ratanatharathorn Chirapha Tannanonta Supron Onsanit Porntip Yuktanonda |
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Lucksana Pochanugool |
title |
Osteosarcoma : A Study of 130 Cases |
title_short |
Osteosarcoma : A Study of 130 Cases |
title_full |
Osteosarcoma : A Study of 130 Cases |
title_fullStr |
Osteosarcoma : A Study of 130 Cases |
title_full_unstemmed |
Osteosarcoma : A Study of 130 Cases |
title_sort |
osteosarcoma : a study of 130 cases |
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2018 |
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https://repository.li.mahidol.ac.th/handle/123456789/18181 |
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1763493463828987904 |