Reduction - Mediated <sup>99m</sup>Tc - Labeling of Antitumor Monoclonal Antibodies : Effect of Increasing Specific Activity on Antibody Binding Kinetics

Reduction-mediated 99mTc-labeling of antibodies has gained widespread acceptance in preparation of tumor imaging agents. Increased specific activity to enhance detection signals has raised the question of whether such an attempt would cause change in antibody binding kinetics. To answer this questio...

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Bibliographic Details
Main Authors: Vipa Boonkitticharoen, Duangpen Puchinda, Puthiporn Chouplywech, Wirawat Jalayondeja
Other Authors: Mahidol University
Format: Article
Published: 2018
Subjects:
Online Access:https://repository.li.mahidol.ac.th/handle/123456789/18470
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Institution: Mahidol University