Structure-activity relationships of some indolo[3,2-c]quinolines with antimalarial activity

The synthesis, physicochemical characterization and in vitro antimalarial activity of a series of indolo[3,2-c]quinolines (9a-f) are described. There is only a poor correlation between the activity and hydrophobicity. In contrast, 33% of the observed variation in antimalarial activity can be attribu...

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Bibliographic Details
Main Authors: Mei Lin Go, Tong Lan Ngiam, Agnes Lay Choo Tan, Kunnika Kuaha, Prapon Wilairat
Other Authors: National University of Singapore
Format: Article
Published: 2018
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Online Access:https://repository.li.mahidol.ac.th/handle/123456789/18638
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Institution: Mahidol University