1-Methyl-4-phenyl-pyridinium ion-induced oxidative stress, c-Jun phosphorylation and DNA fragmentation factor-45 cleavage in SK-N-SH cells are averted by selegiline

1-Methyl-4-phenyl-pyridinium ion-induced oxidative stress, c-Jun phosphorylation and DNA fragmentation factor-45 cleavage in SK-N-SH cells are averted by selegiline

Parkinson's disease is a progressive neurodegenerative disorder, associated with the selective loss of dopaminergic neurons in the substantia nigra pars compacta. Recent studies have shown that c-Jun-N terminal kinase pathways might be involved in the oxidative stress-induced neuronal demise. I...

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Bibliographic Details
Main Authors: Banthit Chetsawang, Patcharee Kooncumchoo, Piyarat Govitrapong, Manuchair Ebadi
Other Authors: The Institute of Science and Technology for Research and Development, Mahidol University
Format: Article
Published: 2018
Subjects:
Biochemistry, Genetics and Molecular Biology
Neuroscience
Online Access:https://repository.li.mahidol.ac.th/handle/123456789/18817
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Institution: Mahidol University

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https://repository.li.mahidol.ac.th/handle/123456789/18817

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