Diarylheptanoids, new phytoestrogens from the rhizomes of Curcuma comosa: Isolation, chemical modification and estrogenic activity evaluation

• Main Authors: Apichart Suksamrarn, Mathurose Ponglikitmongkol, Kanjana Wongkrajang, Anon Chindaduang, Suthadta Kittidanairak, Aroon Jankam, Boon ek Yingyongnarongkul, Narin Kittipanumat, Ratchanaporn Chokchaisiri, Pichit Khetkam, Pawinee Piyachaturawat
• Other Authors: Ramkhamhaeng University
• Format: Article
• Published: 2018
• Subjects: Biochemistry, Genetics and Molecular Biology; Chemistry; Pharmacology, Toxicology and Pharmaceutics
• Online Access: https://repository.li.mahidol.ac.th/handle/123456789/18892
• Institution: Mahidol University

Three new diarylheptanoids, a 1:2 mixture of (3S)- and (3R)-1-(4-methoxyphenyl)-7-phenyl-(6E)-6-hepten-3-ol (13a and 13b) and 1-(4-hydroxyphenyl)-7-phenyl-(6E)-6-hepten-3-one (15), together with two synthetically known diarylheptanoids 1,7-diphenyl-(1E,3E,5E)-1,3,5-triene (9) and 1-(4-hydroxyphenyl)...