A comparative biochemical analysis of the NS2B(H)-NS3pro protease complex from four dengue virus serotypes
The two-component protease NS2B-NS3 of dengue virus mediates proteolytic processing of the polyprotein precursor and therefore represents a target for the development of antiviral drugs. The amino acid sequences of the NS3 serine protease and the NS2B cofactor exhibit relatively low degrees of conse...
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Main Authors: | , , , |
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Format: | Article |
Published: |
2018
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Online Access: | https://repository.li.mahidol.ac.th/handle/123456789/18896 |
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Institution: | Mahidol University |