Investigation of the acid-mediated cyclisation of amide acetal for the synthesis of benzazepinone

On treatment with acids, the open-chained amide acetals (1) gave the 7,7 membered ring fused benzazepinones (4) via the bis-cyclisation. © 2008 The Japan Institute of Heterocyclic Chemistry.

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Bibliographic Details
Main Authors: Wong Phakhodee, Poolsak Sahakitpichan, Songpon Deechongkit, Somsak Ruchirawat
Other Authors: Chulabhorn Research Institute
Format: Article
Published: 2018
Subjects:
Online Access:https://repository.li.mahidol.ac.th/handle/123456789/19074
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Institution: Mahidol University
Description
Summary:On treatment with acids, the open-chained amide acetals (1) gave the 7,7 membered ring fused benzazepinones (4) via the bis-cyclisation. © 2008 The Japan Institute of Heterocyclic Chemistry.