Quantitative determination of 8-hydroxy-2'-deoxyguanosine as a biomarker of oxidative stress in thalassemic patients using HPLC with an electrochemical detector
A simple and robust HPLC method with electrochemical detection was developed for the quantitative determination of 8-hydroxy-2'-deoxyguanosine (8-OHdG), a DNA damage product excreted in urine. Sample cleanup was carried out using solid-phase extraction (SPE) prior to chromatographic separation....
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| Main Authors: | , |
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| Format: | Article |
| Published: |
2018
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| Subjects: | |
| Online Access: | https://repository.li.mahidol.ac.th/handle/123456789/19100 |
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| Institution: | Mahidol University |