Mathematical modeling and application of genetic algorithm to parameter estimation in signal transduction: Trafficking and promiscuous coupling of G-protein coupled receptors

G-protein-coupled receptors (GPCRs) constitute a large and diverse family of proteins whose primary function is to transduce extracellular stimuli into intracellular signals. These receptors play a critical role in signal transduction, and are among the most important pharmacological drug targets. U...

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Bibliographic Details
Main Authors: Charin Modchang, Wannapong Triampo, Yongwimon Lenbury
Other Authors: Mahidol University
Format: Article
Published: 2018
Subjects:
Online Access:https://repository.li.mahidol.ac.th/handle/123456789/19141
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Institution: Mahidol University