Mathematical modeling and application of genetic algorithm to parameter estimation in signal transduction: Trafficking and promiscuous coupling of G-protein coupled receptors
G-protein-coupled receptors (GPCRs) constitute a large and diverse family of proteins whose primary function is to transduce extracellular stimuli into intracellular signals. These receptors play a critical role in signal transduction, and are among the most important pharmacological drug targets. U...
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Main Authors: | , , |
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Format: | Article |
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2018
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Online Access: | https://repository.li.mahidol.ac.th/handle/123456789/19141 |
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Institution: | Mahidol University |