Differential gene expression profiles of human monocyte-derived antigen presenting cells in response to Penicillium marneffei: Roles of DC-SIGN (CD209) in fungal cell uptake

• Main Authors: Piyaporn Ngaosuwankul, Piyapong Pongtanalert, Aneke Engering, Sansanee C. Chaiyaroj
• Other Authors: Mahidol University
• Format: Article
• Published: 2018
• Subjects: Immunology and Microbiology; Medicine
• Online Access: https://repository.li.mahidol.ac.th/handle/123456789/19265

DNA microarray technology was used to determine the gene expression profile of human monocyte-derived macrophages (hMDMs) after stimulation by Penicillium marneffei yeast. The expression levels of 175 macrophage genes were found to be altered by a minimum of two-fold in magnitude following 4 hours o...