Involvement of phospholipase D in regulating expression of anti-microbial peptide human β-defensin-2

• Main Authors: Suttichai Krisanaprakornkit, Pareena Chotjumlong, Prachya Kongtawelert, Vichai Reutrakul
• Other Authors: Chiang Mai University
• Format: Article
• Published: 2018
• Subjects: Immunology and Microbiology
• Online Access: https://repository.li.mahidol.ac.th/handle/123456789/19382
• Institution: Mahidol University

Human β-defensin expression correlates with differentiation in oral epithelium, and calcium ion, an important regulator of epithelial differentiation, plays a critical role in regulation of human β-defensin-2 (hBD-2) mRNA expression. Phospholipase D (PLD) also regulates epithelial differentiation. T...