Pharmacodynamic interaction between monodesbutyl-benflumetol and artemisinin as well as proguanil in Plasmodium falciparum in vitro

Pharmacodynamic interaction between monodesbutyl-benflumetol and artemisinin as well as proguanil in Plasmodium falciparum in vitro

The sensitivity of Plasmodium falciparum against artemisinin, monodebutyl-benflumetol (DBB) and a 1:3 m/m combination of both compounds was assessed in 51 fresh parasite isolates. Although a comparison between fully inhibitory concentrations (GMCOC) of artemisinin alone (63.33 nM), DBB alone (50.15...

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Bibliographic Details
Main Authors: Jens Raffelsberger, Gunther Wernsdorfer, Jeeraphat Sirichaisinthop, Herwig Kollaritsch, Kanungnit Congpuong, Walther H. Wernsdorfer
Other Authors: Medizinische Universitat Wien
Format: Article
Published: 2018
Subjects:
Medicine
Online Access:https://repository.li.mahidol.ac.th/handle/123456789/19520
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Institution: Mahidol University

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https://repository.li.mahidol.ac.th/handle/123456789/19520

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