A model of phenotypic susceptibility to tuberculosis: Deficient in silico selection of Mycobacterium tuberculosis epitopes by HLA alleles

HLA-DR allelic variants have been associated with tuberculosis (TB) susceptibility in different populations with risk ratios of 3.7 to 7.2. We hypothesized that the genetic susceptibility to TB depends upon the reduced capability of HLA-class II alleles of TB patients to bind and select peptide anti...

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Bibliographic Details
Main Authors: S. Contini, M. Pallante, S. Vejbaesya, M. H. Park, N. Chierakul, H. S. Kim, C. Saltini, Massimo Amicosante
Other Authors: Universita degli Studi di Roma Tor Vergata
Format: Article
Published: 2018
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Online Access:https://repository.li.mahidol.ac.th/handle/123456789/19562
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Institution: Mahidol University