Baseline levels of plasma endothelin-1 (ET-1) and changes during transfusion in thalassemic patients

• Main Authors: Vip Viprakasit, Suthida Kankirawatana, Pravit Akarasereenont, Kritvikrom Durongpisitkul, Sirikul Chotewuttakorn, Voravarn S. Tanphaichitr
• Other Authors: Weatherall Institute of Molecular Medicine
• Format: Article
• Published: 2018
• Subjects: Medicine
• Online Access: https://repository.li.mahidol.ac.th/handle/123456789/20462
• Institution: Mahidol University

We studied levels of plasma endothelin-1 (ET-1) in 25 β-thalassemia/Hb E patients before and after blood transfusion. Baseline ET-1 levels in these patients were significantly higher than in normal controls (10.17 ± 2.1 pg/mL vs. 8.9 ± 2.0 pg/mL, P < 0.05). After blood transfusion, levels of plas...