Bone histology and bone mineral density after correction of acidosis in distal renal tubular acidosis

• Main Authors: Somnuek Domrongkitchaiporn, Cholatip Pongskul, Vorachai Sirikulchayanonta, Wasana Stitchantrakul, Virut Leeprasert, Boonsong Ongphiphadhanakul, Piyanuch Radinahamed, Rajata Rajatanavin
• Other Authors: Mahidol University
• Format: Article
• Published: 2018
• Subjects: Medicine
• Online Access: https://repository.li.mahidol.ac.th/handle/123456789/20585

Background. The association between chronic metabolic acidosis and alterations in bone cell functions has been demonstrated in vitro and in animal studies. However, the causal role of acidosis and the effects of alkaline therapy on bone histology and bone mineral density in chronic metabolic acidosi...