Phosphatidylserine exposure in Fas type I cells is mitochondria-dependent

Previous studies have demonstrated that Fas-triggered activation of effector caspases and subsequent nuclear apoptosis either is mitochondria-independent (type I cells) or relies on mitochondrial amplification of the initial stimulus (type II cells). We show herein that Bcl-2 overexpression in a pro...

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Bibliographic Details
Main Authors: Wanlaya Uthaisang, Leta K. Nutt, Sten Orrenius, Bengt Fadeel
Other Authors: Karolinska Institutet
Format: Article
Published: 2018
Subjects:
Online Access:https://repository.li.mahidol.ac.th/handle/123456789/20718
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Institution: Mahidol University