Recombinant PfEMP1 peptide inhibits and reverses cytoadherence of clinical Plasmodium falciparum isolates in vivo

The parasite ligand Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1) and host endothelial receptors represent potential targets for antiadhesive therapy for cytoadherence. In the present study, the major host receptor CD36 was targeted in vitro and in vivo with a recombinant peptide, Pp...

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Bibliographic Details
Main Authors: Bryan G. Yipp, Dror I. Baruch, Ciaran Brady, Allan G. Murray, Sornchai Looareesuwan, Paul Kubes, May Ho
Other Authors: University of Calgary
Format: Article
Published: 2018
Subjects:
Online Access:https://repository.li.mahidol.ac.th/handle/123456789/20788
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Institution: Mahidol University