Failures of 1 week on, 1 week off antiretroviral therapies in a randomized trial

• Main Authors: Jintanat Ananworanich, Reto Nuesch, Michelle Le Braz, Ploechan Chetchotisakd, Asda Vibhagool, Saijai Wicharuk, Kiat Ruxrungtham, Hansjakob Furrer, David Cooper, Bernard Hirschel
• Other Authors: Universitatsspital Basel
• Format: Article
• Published: 2018
• Subjects: Immunology and Microbiology
• Online Access: https://repository.li.mahidol.ac.th/handle/123456789/20875
• Institution: Mahidol University

Background: Scheduled treatment interruptions are being evaluated in an effort to decrease costs and side effects of highly active antiretroviral therapy (HAART). A schedule of 1 week on and 1 week off therapy offers the promise of 50% less drug exposure with continuously undetectable HIV RNA concen...