A randomized comparison of oral chloroquine and sulfadoxine-pyrimethamine for the treatment of uncomplicated Plasmodium falciparum malaria in Laos
Between June and October 2000 we conducted the first randomized trial in Laos comparing chloroquine (CQ) with sulfadoxine-pyrimethamine (SP) in the treatment of uncomplicated Plasmodium falciparum malaria (n = 29, 42-d follow-up, age > 5 years). The proportion of patients with treatment failure w...
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th-mahidol.209072018-07-24T10:25:20Z A randomized comparison of oral chloroquine and sulfadoxine-pyrimethamine for the treatment of uncomplicated Plasmodium falciparum malaria in Laos Mayfong Mayxay Rattanaxay Phetsouvanh Samlane Phompida Paul N. Newton Maniphone Khanthavong Bouakham Vannachone Alan Brockman Nicholas J. White National University of Laos Mahosot Hospital Parasitology and Entomology John Radcliffe Hospital Mahidol University Shoklo Malaria Research Unit Immunology and Microbiology Between June and October 2000 we conducted the first randomized trial in Laos comparing chloroquine (CQ) with sulfadoxine-pyrimethamine (SP) in the treatment of uncomplicated Plasmodium falciparum malaria (n = 29, 42-d follow-up, age > 5 years). The proportion of patients with treatment failure was high (CQ = 78%, RIII 46%; SP = 36%, RIII 15%). The treatment policy for uncomplicated P. falciparum malaria in Laos needs to be reviewed urgently. © 2003 Royal Society of Tropical Medicine and Hygiene. 2018-07-24T03:25:20Z 2018-07-24T03:25:20Z 2003-05-01 Article Transactions of the Royal Society of Tropical Medicine and Hygiene. Vol.97, No.3 (2003), 343-344 10.1016/S0035-9203(03)90165-9 00359203 2-s2.0-4444234983 https://repository.li.mahidol.ac.th/handle/123456789/20907 Mahidol University SCOPUS https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=4444234983&origin=inward |
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Asia |
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Thailand Thailand |
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Immunology and Microbiology |
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Immunology and Microbiology Mayfong Mayxay Rattanaxay Phetsouvanh Samlane Phompida Paul N. Newton Maniphone Khanthavong Bouakham Vannachone Alan Brockman Nicholas J. White A randomized comparison of oral chloroquine and sulfadoxine-pyrimethamine for the treatment of uncomplicated Plasmodium falciparum malaria in Laos |
| description |
Between June and October 2000 we conducted the first randomized trial in Laos comparing chloroquine (CQ) with sulfadoxine-pyrimethamine (SP) in the treatment of uncomplicated Plasmodium falciparum malaria (n = 29, 42-d follow-up, age > 5 years). The proportion of patients with treatment failure was high (CQ = 78%, RIII 46%; SP = 36%, RIII 15%). The treatment policy for uncomplicated P. falciparum malaria in Laos needs to be reviewed urgently. © 2003 Royal Society of Tropical Medicine and Hygiene. |
| author2 |
National University of Laos |
| author_facet |
National University of Laos Mayfong Mayxay Rattanaxay Phetsouvanh Samlane Phompida Paul N. Newton Maniphone Khanthavong Bouakham Vannachone Alan Brockman Nicholas J. White |
| format |
Article |
| author |
Mayfong Mayxay Rattanaxay Phetsouvanh Samlane Phompida Paul N. Newton Maniphone Khanthavong Bouakham Vannachone Alan Brockman Nicholas J. White |
| author_sort |
Mayfong Mayxay |
| title |
A randomized comparison of oral chloroquine and sulfadoxine-pyrimethamine for the treatment of uncomplicated Plasmodium falciparum malaria in Laos |
| title_short |
A randomized comparison of oral chloroquine and sulfadoxine-pyrimethamine for the treatment of uncomplicated Plasmodium falciparum malaria in Laos |
| title_full |
A randomized comparison of oral chloroquine and sulfadoxine-pyrimethamine for the treatment of uncomplicated Plasmodium falciparum malaria in Laos |
| title_fullStr |
A randomized comparison of oral chloroquine and sulfadoxine-pyrimethamine for the treatment of uncomplicated Plasmodium falciparum malaria in Laos |
| title_full_unstemmed |
A randomized comparison of oral chloroquine and sulfadoxine-pyrimethamine for the treatment of uncomplicated Plasmodium falciparum malaria in Laos |
| title_sort |
randomized comparison of oral chloroquine and sulfadoxine-pyrimethamine for the treatment of uncomplicated plasmodium falciparum malaria in laos |
| publishDate |
2018 |
| url |
https://repository.li.mahidol.ac.th/handle/123456789/20907 |
| _version_ |
1763489336374853632 |