The effectiveness of cucurbitacin B in BRCA1 defective breast cancer cells

• Main Authors: Moltira Promkan, Sumana Dakeng, Subhas Chakrabarty, Oliver Bögler, Pimpicha Patmasiriwat
• Other Authors: Mahidol University. Faculty of Medical Technology
• Format: Article
• Language: English
• Published: Mahidol University 2014
• Subjects: Breast tumors; Cancer prevention; Cancer treatment; Cancers and neoplasms; Chemotherapy and drug treatment; Drug discovery; Drug research and development; Molecular cell biology; Oncology; Pharmacology
• Online Access: https://repository.li.mahidol.ac.th/handle/123456789/2103
• Institution: Mahidol University

Cucurbitacin B (CuB) is one of the potential agents for long term anticancer chemoprevention. Cumulative evidences has shown that cucurbitacin B provides potent cellular biological activities such as hepatoprotective, anti-inflammatory and antimicrobial effects, but the precise mechanism of this age...